Adjuvant Methods to Improve Results of Local Bladder Irrigations by Chemotherapy for NMIBC
Freifeld Y, Dekel Y, Stein A.CurrUrol Rep. 2013 Jan 19. [Epub ahead of print]

Source

Department of Urology, Carmel Medical Centre, 7 Michal Street, Haifa, Israel, Yuvalfr@clalit.org.il.

Abstract

Non-muscle-invasive bladder cancer is characterized by frequent recurrences requiring repeated transurethral resections and carries a risk of progression to muscle-invasive disease. The routinely used, passive diffusion irrigation of the bladder with mitomycin C has achieved limited success in avoiding these events. We review two methods that may improve penetration of mitomycin C into the bladder wall, thus leading to better results in terms of recurrence rate and bladder preservation.