Tolterodine for the treatment of urge urinary incontinence
Elterman DS, Chughtai B, Kaplan SA, Barkin J. Expert Opin Pharmacother. 2013 Jul 26. [Epub ahead of print]


Weill Cornell Medical College of Cornell University, James Buchanan Brady Department of Urology , 425 East 61st Street, 12th floor, New York, NY 10065 , USA.


Introduction: Overactive bladder (OAB) and its resultant urge urinary incontinence (UUI) are significant problems that medically, psychologically and financially affect people. The constellation of symptoms comprising OAB affects ∼ 16% of the adult population and its prevalence increases with aging. The typical class of medications used to treat OAB is antimuscarinics. Areas covered: OAB medications, with a focus on tolterodine for the treatment of UUI are reviewed. A thorough review of English language literature using EMBASE/Medline and PubMed has been performed. Expert opinion: Tolterodine provides a reasonable starting point when treating patients with OAB and UUI. Efficacy and tolerability are generally comparable between tolterodine and other newer antimuscarinics. Tolterodine is a good option as part of the algorithm in the treatment of OAB and UUI.